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  1. Currently recruiting

UK-ROX

Intensive Care Unit Randomised Trial Comparing Two Approaches to OXygen Therapy

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Last updated 2 years ago

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PICO Question

  • Population: ICU patients requiring mechanical ventilation with supplementary oxygen

  • Interventions: Conservative oxygen therapy (SpO2 88-92%)

  • Comparison: Usual care

  • Outcomes: 90-day mortality

Recruitment

Inclusion criteria

Exclusion criteria

  • Aged ≥18 years

  • Receiving IPPV following unplanned admission or IPPV started in ICU

  • Receiving FiO2 >0.21

  • Previously in UK-ROX in the last 90 days

  • Currently receiving ECMO

  • One intervention arm specifically indicated/contraindicated

Details

  • Principle investigator: Dan Harvey

  • Trainee-lead:

  • DREEAM: David Ford

Website:

FAQ section on website helpful in interpreting exclusion criteria ()

https://www.icnarc.org/Our-Research/Studies/Uk-Rox
https://www.icnarc.org/Our-Research/Studies/Uk-Rox/Information-For-Sites/Faqs